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Review on Structures of Pesticide Targets
Molecular targets play important roles in agrochemical discovery. Numerous pesticides target the key proteins in pathogens, insect, or plants. Investigating ligand-binding pockets and/or active sites in the proteins’ structures is usually the first step in designing new green pesticides. Thus, molec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582455/ https://www.ncbi.nlm.nih.gov/pubmed/32998191 http://dx.doi.org/10.3390/ijms21197144 |
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author | Li, Xiangyang Yang, Xueqing Zheng, Xiaodong Bai, Miao Hu, Deyu |
author_facet | Li, Xiangyang Yang, Xueqing Zheng, Xiaodong Bai, Miao Hu, Deyu |
author_sort | Li, Xiangyang |
collection | PubMed |
description | Molecular targets play important roles in agrochemical discovery. Numerous pesticides target the key proteins in pathogens, insect, or plants. Investigating ligand-binding pockets and/or active sites in the proteins’ structures is usually the first step in designing new green pesticides. Thus, molecular target structures are extremely important for the discovery and development of such pesticides. In this manuscript, we present a review of the molecular target structures, including those of antiviral, fungicidal, bactericidal, insecticidal, herbicidal, and plant growth-regulator targets, currently used in agrochemical research. The data will be helpful in pesticide design and the discovery of new green pesticides. |
format | Online Article Text |
id | pubmed-7582455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75824552020-10-29 Review on Structures of Pesticide Targets Li, Xiangyang Yang, Xueqing Zheng, Xiaodong Bai, Miao Hu, Deyu Int J Mol Sci Review Molecular targets play important roles in agrochemical discovery. Numerous pesticides target the key proteins in pathogens, insect, or plants. Investigating ligand-binding pockets and/or active sites in the proteins’ structures is usually the first step in designing new green pesticides. Thus, molecular target structures are extremely important for the discovery and development of such pesticides. In this manuscript, we present a review of the molecular target structures, including those of antiviral, fungicidal, bactericidal, insecticidal, herbicidal, and plant growth-regulator targets, currently used in agrochemical research. The data will be helpful in pesticide design and the discovery of new green pesticides. MDPI 2020-09-28 /pmc/articles/PMC7582455/ /pubmed/32998191 http://dx.doi.org/10.3390/ijms21197144 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Li, Xiangyang Yang, Xueqing Zheng, Xiaodong Bai, Miao Hu, Deyu Review on Structures of Pesticide Targets |
title | Review on Structures of Pesticide Targets |
title_full | Review on Structures of Pesticide Targets |
title_fullStr | Review on Structures of Pesticide Targets |
title_full_unstemmed | Review on Structures of Pesticide Targets |
title_short | Review on Structures of Pesticide Targets |
title_sort | review on structures of pesticide targets |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582455/ https://www.ncbi.nlm.nih.gov/pubmed/32998191 http://dx.doi.org/10.3390/ijms21197144 |
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