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Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition

The interaction between T cell receptor (TCR) and peptide (p)-Human Leukocyte Antigen (HLA) complexes is the critical first step in determining T cell responses. X-ray crystallographic studies of pHLA in TCR-bound and free states provide a structural perspective that can help understand T cell activ...

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Detalles Bibliográficos
Autores principales:	Szeto, Christopher, Bloom, Joseph I., Sloane, Hannah, Lobos, Christian A., Fodor, James, Jayasinghe, Dhilshan, Chatzileontiadou, Demetra S. M., Grant, Emma J., Buckle, Ashley M., Gras, Stephanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582474/ https://www.ncbi.nlm.nih.gov/pubmed/32992915 http://dx.doi.org/10.3390/ijms21197081

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