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The Impact of Drosophila Awd/NME1/2 Levels on Notch and Wg Signaling Pathways

Awd, the Drosophila homologue of NME1/2 metastasis suppressors, plays key roles in many signaling pathways. Mosaic analysis of the null awd(J2A4) allele showed that loss of awd gene function blocks Notch signaling and the expression of its target genes including the Wingless (Wg/Wnt1) morphogen. We...

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Detalles Bibliográficos
Autores principales: Serafini, Giulia, Giordani, Giorgia, Grillini, Luca, Andrenacci, Davide, Gargiulo, Giuseppe, Cavaliere, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582475/
https://www.ncbi.nlm.nih.gov/pubmed/33019537
http://dx.doi.org/10.3390/ijms21197257