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The Impact of Drosophila Awd/NME1/2 Levels on Notch and Wg Signaling Pathways
Awd, the Drosophila homologue of NME1/2 metastasis suppressors, plays key roles in many signaling pathways. Mosaic analysis of the null awd(J2A4) allele showed that loss of awd gene function blocks Notch signaling and the expression of its target genes including the Wingless (Wg/Wnt1) morphogen. We...
Autores principales: | Serafini, Giulia, Giordani, Giorgia, Grillini, Luca, Andrenacci, Davide, Gargiulo, Giuseppe, Cavaliere, Valeria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582475/ https://www.ncbi.nlm.nih.gov/pubmed/33019537 http://dx.doi.org/10.3390/ijms21197257 |
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