Cargando…

Modular Chimeric Antigen Receptor Systems for Universal CAR T Cell Retargeting

The engineering of T cells through expression of chimeric antigen receptors (CARs) against tumor-associated antigens (TAAs) has shown significant potential for use as an anti-cancer therapeutic. The development of strategies for flexible and modular CAR T systems is accelerating, allowing for multip...

Descripción completa

Detalles Bibliográficos
Autores principales: Sutherland, Ashley R., Owens, Madeline N., Geyer, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582510/
https://www.ncbi.nlm.nih.gov/pubmed/33007850
http://dx.doi.org/10.3390/ijms21197222