A Novel Series of [1,2,4]Triazolo[4,3-a]Pyridine Sulfonamides as Potential Antimalarial Agents: In Silico Studies, Synthesis and In Vitro Evaluation

For the development of new and potent antimalarial drugs, we designed the virtual library with three points of randomization of novel [1,2,4]triazolo[4,3-a]pyridines bearing a sulfonamide fragment. The library of 1561 compounds has been investigated by both virtual screening and molecular docking me...

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Detalles Bibliográficos
Autores principales: Karpina, Veronika R., Kovalenko, Svitlana S., Kovalenko, Sergiy M., Drushlyak, Oleksandr G., Bunyatyan, Natalya D., Georgiyants, Victoriya A., Ivanov, Vladimir V., Langer, Thierry, Maes, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582516/
https://www.ncbi.nlm.nih.gov/pubmed/33007887
http://dx.doi.org/10.3390/molecules25194485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582516/
https://www.ncbi.nlm.nih.gov/pubmed/33007887
http://dx.doi.org/10.3390/molecules25194485

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