Cargando…
Drug Development and the Use of Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Disease Modeling and Drug Toxicity Screening
Over the years, numerous groups have employed human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) as a superb human-compatible model for investigating the function and dysfunction of cardiomyocytes, drug screening and toxicity, disease modeling and for the development of novel drug...
Autores principales: | Ovics, Paz, Regev, Danielle, Baskin, Polina, Davidor, Mor, Shemer, Yuval, Neeman, Shunit, Ben-Haim, Yael, Binah, Ofer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582587/ https://www.ncbi.nlm.nih.gov/pubmed/33023024 http://dx.doi.org/10.3390/ijms21197320 |
Ejemplares similares
-
Investigating LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Shemer, Yuval, et al.
Publicado: (2021) -
Electrophysiological abnormalities in induced pluripotent stem cell‐derived cardiomyocytes generated from Duchenne muscular dystrophy patients
por: Eisen, Binyamin, et al.
Publicado: (2019) -
Depressed β‐adrenergic inotropic responsiveness and intracellular calcium handling abnormalities in Duchenne Muscular Dystrophy patients’ induced pluripotent stem cell–derived cardiomyocytes
por: Mekies, Lucy N., et al.
Publicado: (2021) -
Modeling Duchenne Muscular Dystrophy Cardiomyopathy with Patients’ Induced Pluripotent Stem-Cell-Derived Cardiomyocytes
por: Eisen, Binyamin, et al.
Publicado: (2023) -
Bioenergetic and Metabolic Impairments in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Generated from Duchenne Muscular Dystrophy Patients
por: Willi, Lubna, et al.
Publicado: (2022)