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Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes
Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the livin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582750/ https://www.ncbi.nlm.nih.gov/pubmed/33019606 http://dx.doi.org/10.3390/molecules25194502 |
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author | Ishihara, Masayuki Hata, Yuuki Hiruma, Sumiyo Takayama, Tomohiro Nakamura, Shingo Sato, Yoko Ando, Naoko Fukuda, Koichi Murakami, Kaoru Yokoe, Hidetaka |
author_facet | Ishihara, Masayuki Hata, Yuuki Hiruma, Sumiyo Takayama, Tomohiro Nakamura, Shingo Sato, Yoko Ando, Naoko Fukuda, Koichi Murakami, Kaoru Yokoe, Hidetaka |
author_sort | Ishihara, Masayuki |
collection | PubMed |
description | Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the living body, given the strong alkalinity. This study aimed to investigate the safety of BiSCaO Water for use as an antiseptic/disinfectant despite concerns regarding its high alkalinity. The change over time in pH of BiSCaO Water was measured during air contact (stirring BiSCaO Water in ambient air). When sprayed on metal, plastic, wood piece, paper, and skin surfaces, the pH of BiSCaO Water decreased rapidly, providing a white powder coating upon drying. Scanning electron microscopy images, energy dispersive X-ray elemental mapping, and X-ray diffractograms showed that the dried powder residues of BiSCaO Water were composed primarily of calcium carbonate. These results suggested that BiSCaO Water is a potent reagent that may overcome the obstacles of being strongly alkaline, making this material appropriate for use in disinfection against pathogenic microbes. |
format | Online Article Text |
id | pubmed-7582750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75827502020-10-28 Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes Ishihara, Masayuki Hata, Yuuki Hiruma, Sumiyo Takayama, Tomohiro Nakamura, Shingo Sato, Yoko Ando, Naoko Fukuda, Koichi Murakami, Kaoru Yokoe, Hidetaka Molecules Article Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the living body, given the strong alkalinity. This study aimed to investigate the safety of BiSCaO Water for use as an antiseptic/disinfectant despite concerns regarding its high alkalinity. The change over time in pH of BiSCaO Water was measured during air contact (stirring BiSCaO Water in ambient air). When sprayed on metal, plastic, wood piece, paper, and skin surfaces, the pH of BiSCaO Water decreased rapidly, providing a white powder coating upon drying. Scanning electron microscopy images, energy dispersive X-ray elemental mapping, and X-ray diffractograms showed that the dried powder residues of BiSCaO Water were composed primarily of calcium carbonate. These results suggested that BiSCaO Water is a potent reagent that may overcome the obstacles of being strongly alkaline, making this material appropriate for use in disinfection against pathogenic microbes. MDPI 2020-10-01 /pmc/articles/PMC7582750/ /pubmed/33019606 http://dx.doi.org/10.3390/molecules25194502 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ishihara, Masayuki Hata, Yuuki Hiruma, Sumiyo Takayama, Tomohiro Nakamura, Shingo Sato, Yoko Ando, Naoko Fukuda, Koichi Murakami, Kaoru Yokoe, Hidetaka Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title | Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title_full | Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title_fullStr | Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title_full_unstemmed | Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title_short | Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes |
title_sort | safety of concentrated bioshell calcium oxide water application for surface and skin disinfections against pathogenic microbes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582750/ https://www.ncbi.nlm.nih.gov/pubmed/33019606 http://dx.doi.org/10.3390/molecules25194502 |
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