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Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo

Here, we evaluated the effects of PEDF (pigment epithelium-derived factor) and PEDF peptides on cone-photoreceptor cell damage in a mouse model of focal LED-induced phototoxicity (LIP) in vivo. Swiss mice were dark-adapted overnight, anesthetized, and their left eyes were exposed to a blue LED place...

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Detalles Bibliográficos
Autores principales: Valiente-Soriano, Francisco J., Di Pierdomenico, Johnny, García-Ayuso, Diego, Ortín-Martínez, Arturo, Miralles de Imperial-Ollero, Juan A., Gallego-Ortega, Alejandro, Jiménez-López, Manuel, Villegas-Pérez, M. Paz, Becerra, S. Patricia, Vidal-Sanz, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582775/
https://www.ncbi.nlm.nih.gov/pubmed/33008127
http://dx.doi.org/10.3390/ijms21197242

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