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Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo
Here, we evaluated the effects of PEDF (pigment epithelium-derived factor) and PEDF peptides on cone-photoreceptor cell damage in a mouse model of focal LED-induced phototoxicity (LIP) in vivo. Swiss mice were dark-adapted overnight, anesthetized, and their left eyes were exposed to a blue LED place...
Autores principales: | Valiente-Soriano, Francisco J., Di Pierdomenico, Johnny, García-Ayuso, Diego, Ortín-Martínez, Arturo, Miralles de Imperial-Ollero, Juan A., Gallego-Ortega, Alejandro, Jiménez-López, Manuel, Villegas-Pérez, M. Paz, Becerra, S. Patricia, Vidal-Sanz, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582775/ https://www.ncbi.nlm.nih.gov/pubmed/33008127 http://dx.doi.org/10.3390/ijms21197242 |
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