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Huisgen [3 + 2] Dipolar Cycloadditions of Phthalazinium Ylides to Activated Symmetric and Non-Symmetric Alkynes

We present herein a straightforward and efficient pathway for the synthesis of pyrrolophthalazine cycloadducts via Huisgen [3 + 2] dipolar cycloaddition reactions of phthalazinium ylides to methyl propiolate or dimethyl acetylenedicarboxylate (DMAD). A thoroughly comparative study concerning the eff...

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Detalles Bibliográficos
Autores principales:	Antoci, Vasilichia, Moldoveanu, Costel, Danac, Ramona, Mangalagiu, Violeta, Zbancioc, Gheorghita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582813/ https://www.ncbi.nlm.nih.gov/pubmed/32992961 http://dx.doi.org/10.3390/molecules25194416

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