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Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

A group of triethylphosphine gold(I) and silver(I) complexes, structurally related to auranofin, were prepared and investigated as potential anticancer drug candidates. The antiproliferative properties of these metal compounds were assessed against two leukemia cell lines, i.e., CCRF-CEM and its mul...

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Detalles Bibliográficos
Autores principales: Cirri, Damiano, Schirmeister, Tanja, Seo, Ean-Jeong, Efferth, Thomas, Massai, Lara, Messori, Luigi, Micale, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582876/
https://www.ncbi.nlm.nih.gov/pubmed/32998355
http://dx.doi.org/10.3390/molecules25194454

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