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Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity

Brown adipose tissue (BAT) is an important target for obesity treatment and prevention. Soluble epoxide hydrolase (sEH) converts bioactive epoxy fatty acids (EpFAs) into less active diols. sEH inhibitors (sEHI) are beneficial in many chronic diseases by stabilizing EpFAs. However, roles of sEH and s...

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Detalles Bibliográficos
Autores principales: Overby, Haley, Yang, Yang, Xu, Xinyun, Graham, Katherine, Hildreth, Kelsey, Choi, Sue, Wan, Debin, Morisseau, Christophe, Zeldin, Darryl C., Hammock, Bruce D., Wang, Shu, Bettaieb, Ahmed, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582898/
https://www.ncbi.nlm.nih.gov/pubmed/32987880
http://dx.doi.org/10.3390/ijms21197039