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Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity
Brown adipose tissue (BAT) is an important target for obesity treatment and prevention. Soluble epoxide hydrolase (sEH) converts bioactive epoxy fatty acids (EpFAs) into less active diols. sEH inhibitors (sEHI) are beneficial in many chronic diseases by stabilizing EpFAs. However, roles of sEH and s...
Autores principales: | Overby, Haley, Yang, Yang, Xu, Xinyun, Graham, Katherine, Hildreth, Kelsey, Choi, Sue, Wan, Debin, Morisseau, Christophe, Zeldin, Darryl C., Hammock, Bruce D., Wang, Shu, Bettaieb, Ahmed, Zhao, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582898/ https://www.ncbi.nlm.nih.gov/pubmed/32987880 http://dx.doi.org/10.3390/ijms21197039 |
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