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Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington’s Disease Status Based on Omics Data
Huntington’s disease is a rare neurodegenerative disease caused by a cytosine–adenine–guanine (CAG) trinucleotide expansion in the Huntingtin (HTT) gene. Although Huntington’s disease (HD) is well studied, the pathophysiological mechanisms, genes and metabolites involved in HD remain poorly understo...
Autores principales: | Christodoulou, Christiana C., Zachariou, Margarita, Tomazou, Marios, Karatzas, Evangelos, Demetriou, Christiana A., Zamba-Papanicolaou, Eleni, Spyrou, George M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582902/ https://www.ncbi.nlm.nih.gov/pubmed/33049985 http://dx.doi.org/10.3390/ijms21197414 |
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