Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome

Atrioventricular septal defects (AVSD) are a severe congenital heart defect present in individuals with Down syndrome (DS) at a > 2000-fold increased prevalence compared to the general population. This study aimed to identify risk-associated genes and pathways and to examine a potential polygenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Trevino, Cristina E., Holleman, Aaron M., Corbitt, Holly, Maslen, Cheryl L., Rosser, Tracie C., Cutler, David J., Johnston, H. Richard, Rambo-Martin, Benjamin L., Oberoi, Jai, Dooley, Kenneth J., Capone, George T., Reeves, Roger H., Cordell, Heather J., Keavney, Bernard D., Agopian, A.J., Goldmuntz, Elizabeth, Gruber, Peter J., O’Brien, James E., Bittel, Douglas C., Wadhwa, Lalita, Cua, Clifford L., Moskowitz, Ivan P., Mulle, Jennifer G., Epstein, Michael P., Sherman, Stephanie L., Zwick, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582922/
https://www.ncbi.nlm.nih.gov/pubmed/33093519
http://dx.doi.org/10.1038/s41598-020-74650-4

Ejemplares similares

Ejemplares similares