Spatial cell type composition in normal and Alzheimers human brains is revealed using integrated mouse and human single cell RNA sequencing

Single-cell RNA sequencing (scRNA-seq) resolves heterogenous cell populations in tissues and helps to reveal single-cell level function and dynamics. In neuroscience, the rarity of brain tissue is the bottleneck for such study. Evidence shows that, mouse and human share similar cell type gene marker...

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Detalles Bibliográficos
Autores principales: Johnson, Travis S., Xiang, Shunian, Helm, Bryan R., Abrams, Zachary B., Neidecker, Peter, Machiraju, Raghu, Zhang, Yan, Huang, Kun, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582925/
https://www.ncbi.nlm.nih.gov/pubmed/33093481
http://dx.doi.org/10.1038/s41598-020-74917-w

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