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Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA Synthetases Dedicated to Aromatic Amino Acids

In protein engineering and synthetic biology, Methanosarcina mazei pyrrolysyl-tRNA synthetase (MmPylRS), with its cognate tRNA(Pyl), is one of the most popular tools for site-specific incorporation of non-canonical amino acids (ncAAs). Numerous orthogonal pairs based on engineered MmPylRS variants h...

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Detalles Bibliográficos
Autores principales:	Tseng, Hsueh-Wei, Baumann, Tobias, Sun, Huan, Wang, Yane-Shih, Ignatova, Zoya, Budisa, Nediljko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582959/ https://www.ncbi.nlm.nih.gov/pubmed/32992991 http://dx.doi.org/10.3390/molecules25194418

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