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The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders
Prion diseases are fatal and transmissible neurodegenerative diseases in which the cellular form of the prion protein ‘PrP(c)’, misfolds into an infectious and aggregation prone isoform termed PrP(Sc), which is the primary component of prions. Many neurodegenerative diseases, like Alzheimer’s diseas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582986/ https://www.ncbi.nlm.nih.gov/pubmed/32977678 http://dx.doi.org/10.3390/ijms21197016 |