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Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins

Human apurinic/apyrimidinic endonuclease 1 (APE1) is known to be a critical player of the base excision repair (BER) pathway. In general, BER involves consecutive actions of DNA glycosylases, AP endonucleases, DNA polymerases, and DNA ligases. It is known that these proteins interact with APE1 eithe...

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Detalles Bibliográficos
Autores principales:	Kladova, Olga A., Alekseeva, Irina V., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583023/ https://www.ncbi.nlm.nih.gov/pubmed/32998246 http://dx.doi.org/10.3390/ijms21197147

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