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AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery
Scar formation can cause the failure of glaucoma filtration surgery. We investigated the effect of AR12286, a selective Rho-associated kinase inhibitor, on myofibroblast transdifferentiation and intraocular pressure assessment in rabbit glaucoma filtration surgery models. Cell migration and collagen...
Autores principales: | Cheng, Wen-Sheng, Chen, Ching-Long, Chen, Jiann-Torng, Lin, Le-Tien, Pao, Shu-I, Chen, Yi-Hao, Lu, Da-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583051/ https://www.ncbi.nlm.nih.gov/pubmed/32993110 http://dx.doi.org/10.3390/molecules25194422 |
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