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Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report

Phyllodes tumours (PTs) are rare fibroepithelial tumours of the breast with incidence accounting for <1% in the general population. Availability of reports on PTs with size of 31 cm or more in diameter in the literature are extremely rare. Herein, the case of a 17-year-old female patient with a g...

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Autor principal: Yahaya, James J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583418/
https://www.ncbi.nlm.nih.gov/pubmed/33133622
http://dx.doi.org/10.1093/omcr/omaa089
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author Yahaya, James J
author_facet Yahaya, James J
author_sort Yahaya, James J
collection PubMed
description Phyllodes tumours (PTs) are rare fibroepithelial tumours of the breast with incidence accounting for <1% in the general population. Availability of reports on PTs with size of 31 cm or more in diameter in the literature are extremely rare. Herein, the case of a 17-year-old female patient with a giant recurrent right breast PT is reported. Histologically, the tumour showed proliferation of stromal tumour cells consisting of spindle cells with uniform nuclear chromatin, inconspicuous nucleoli, abundant eosinophilic cytoplasm and proliferation labelling index for Ki67 of <10%. PTs require meticulous surgical excision due to the fact that they have a high rate of recurrence and status of surgical margins must be included in the pathology report. This is because recurrent cases of PTs tend to grow faster than the primary ones with a high chance of transforming to malignancy.
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spelling pubmed-75834182020-10-29 Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report Yahaya, James J Oxf Med Case Reports Case Report Phyllodes tumours (PTs) are rare fibroepithelial tumours of the breast with incidence accounting for <1% in the general population. Availability of reports on PTs with size of 31 cm or more in diameter in the literature are extremely rare. Herein, the case of a 17-year-old female patient with a giant recurrent right breast PT is reported. Histologically, the tumour showed proliferation of stromal tumour cells consisting of spindle cells with uniform nuclear chromatin, inconspicuous nucleoli, abundant eosinophilic cytoplasm and proliferation labelling index for Ki67 of <10%. PTs require meticulous surgical excision due to the fact that they have a high rate of recurrence and status of surgical margins must be included in the pathology report. This is because recurrent cases of PTs tend to grow faster than the primary ones with a high chance of transforming to malignancy. Oxford University Press 2020-10-23 /pmc/articles/PMC7583418/ /pubmed/33133622 http://dx.doi.org/10.1093/omcr/omaa089 Text en © The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Yahaya, James J
Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title_full Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title_fullStr Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title_full_unstemmed Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title_short Recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
title_sort recurrent giant phyllodes tumour in a 17-year-old female: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583418/
https://www.ncbi.nlm.nih.gov/pubmed/33133622
http://dx.doi.org/10.1093/omcr/omaa089
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