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Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial
BACKGROUND: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical performance. METHODS: We conducted a randomised, doubl...
Autores principales: | Witham, Miles D, Clarke, Clare L, Hutcheon, Anita, Gingles, Christopher, Gandy, Stephen, Priba, Lukasz, Nicholas, Richard S, Cavin, Ian, Sumukadas, Deepa, Struthers, Allan D, George, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583523/ https://www.ncbi.nlm.nih.gov/pubmed/32318695 http://dx.doi.org/10.1093/ageing/afaa061 |
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