In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist

• In situ pulmonary thrombosis may exist in COVID-19 pneumonia patients with the feature of peripheral distribution. • Some thrombi located just within the consolidation lesions of the infected lungs, likely due to active local inflammation. • Some thrombi located in non-consolidation area, likely d...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Chen, Fei, Bai, Lang, Yi, Qun, Peng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Letter to the Editors-in-Chief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583621/
https://www.ncbi.nlm.nih.gov/pubmed/33129037
http://dx.doi.org/10.1016/j.thromres.2020.10.022
Descripción
Sumario:• In situ pulmonary thrombosis may exist in COVID-19 pneumonia patients with the feature of peripheral distribution. • Some thrombi located just within the consolidation lesions of the infected lungs, likely due to active local inflammation. • Some thrombi located in non-consolidation area, likely due to hypercoagulability caused by systemic inflammation. • We hypothesize different phenotypes of in situ thrombosis may exist and need different intensity of anticoagulant therapy.

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