In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist

• In situ pulmonary thrombosis may exist in COVID-19 pneumonia patients with the feature of peripheral distribution. • Some thrombi located just within the consolidation lesions of the infected lungs, likely due to active local inflammation. • Some thrombi located in non-consolidation area, likely d...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Chen, Fei, Bai, Lang, Yi, Qun, Peng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Letter to the Editors-in-Chief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583621/
https://www.ncbi.nlm.nih.gov/pubmed/33129037
http://dx.doi.org/10.1016/j.thromres.2020.10.022
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author Wang, Lan
Chen, Fei
Bai, Lang
Yi, Qun
Peng, Yong
author_facet Wang, Lan
Chen, Fei
Bai, Lang
Yi, Qun
Peng, Yong
author_sort Wang, Lan
collection PubMed
description • In situ pulmonary thrombosis may exist in COVID-19 pneumonia patients with the feature of peripheral distribution. • Some thrombi located just within the consolidation lesions of the infected lungs, likely due to active local inflammation. • Some thrombi located in non-consolidation area, likely due to hypercoagulability caused by systemic inflammation. • We hypothesize different phenotypes of in situ thrombosis may exist and need different intensity of anticoagulant therapy.
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spelling pubmed-75836212020-10-26 In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist Wang, Lan Chen, Fei Bai, Lang Yi, Qun Peng, Yong Thromb Res Letter to the Editors-in-Chief • In situ pulmonary thrombosis may exist in COVID-19 pneumonia patients with the feature of peripheral distribution. • Some thrombi located just within the consolidation lesions of the infected lungs, likely due to active local inflammation. • Some thrombi located in non-consolidation area, likely due to hypercoagulability caused by systemic inflammation. • We hypothesize different phenotypes of in situ thrombosis may exist and need different intensity of anticoagulant therapy. Elsevier Ltd. 2020-12 2020-10-23 /pmc/articles/PMC7583621/ /pubmed/33129037 http://dx.doi.org/10.1016/j.thromres.2020.10.022 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editors-in-Chief
Wang, Lan
Chen, Fei
Bai, Lang
Yi, Qun
Peng, Yong
In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title_full In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title_fullStr In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title_full_unstemmed In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title_short In situ pulmonary thrombosis in patients with COVID-19 pneumonia: different phenotypes may exist
title_sort in situ pulmonary thrombosis in patients with covid-19 pneumonia: different phenotypes may exist
topic Letter to the Editors-in-Chief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583621/
https://www.ncbi.nlm.nih.gov/pubmed/33129037
http://dx.doi.org/10.1016/j.thromres.2020.10.022
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