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Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy

BACKGROUND: Antibodies against epidermal growth factor receptor (EGFR), panitumumab, a fully human monoclonal antibody, and cetuximab, a human/mouse chimeric monoclonal antibody, have shown clinical efficacy in metastatic colorectal cancer (mCRC). In the phase 3 noninferiority ASPECCT (ClinicalTrial...

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Detalles Bibliográficos
Autores principales:	Price, Timothy, Ang, Agnes, Boedigheimer, Michael, Kim, Tae Won, Li, Jin, Cascinu, Stefano, Ruff, Paul, Satya Suresh, Attili, Thomas, Anne, Tjulandin, Sergei, Peeters, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583702/ https://www.ncbi.nlm.nih.gov/pubmed/33026965 http://dx.doi.org/10.1080/15384047.2020.1798695

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