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The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series

BACKGROUND: The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. CASE REPORT: We reported five individuals with cerebel...

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Detalles Bibliográficos
Autores principales: Amokrane, Nadia, Lin, Chi-Ying R., Desai, Natasha A., Kuo, Sheng-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583703/
https://www.ncbi.nlm.nih.gov/pubmed/33133767
http://dx.doi.org/10.5334/tohm.550
Descripción
Sumario:BACKGROUND: The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. CASE REPORT: We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling. DISCUSSION: These five cases provide examples of behavioral symptoms in cerebellar ataxia. Further investigations of the pathomechanism of these symptoms will advance our understanding of the cerebellum in cognition and behavior.