The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series

BACKGROUND: The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. CASE REPORT: We reported five individuals with cerebel...

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Autores principales: Amokrane, Nadia, Lin, Chi-Ying R., Desai, Natasha A., Kuo, Sheng-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583703/
https://www.ncbi.nlm.nih.gov/pubmed/33133767
http://dx.doi.org/10.5334/tohm.550
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author Amokrane, Nadia
Lin, Chi-Ying R.
Desai, Natasha A.
Kuo, Sheng-Han
author_facet Amokrane, Nadia
Lin, Chi-Ying R.
Desai, Natasha A.
Kuo, Sheng-Han
author_sort Amokrane, Nadia
collection PubMed
description BACKGROUND: The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. CASE REPORT: We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling. DISCUSSION: These five cases provide examples of behavioral symptoms in cerebellar ataxia. Further investigations of the pathomechanism of these symptoms will advance our understanding of the cerebellum in cognition and behavior.
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spelling pubmed-75837032020-10-30 The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series Amokrane, Nadia Lin, Chi-Ying R. Desai, Natasha A. Kuo, Sheng-Han Tremor Other Hyperkinet Mov (N Y) Case Report BACKGROUND: The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. CASE REPORT: We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling. DISCUSSION: These five cases provide examples of behavioral symptoms in cerebellar ataxia. Further investigations of the pathomechanism of these symptoms will advance our understanding of the cerebellum in cognition and behavior. Ubiquity Press 2020-10-16 /pmc/articles/PMC7583703/ /pubmed/33133767 http://dx.doi.org/10.5334/tohm.550 Text en Copyright: © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Case Report
Amokrane, Nadia
Lin, Chi-Ying R.
Desai, Natasha A.
Kuo, Sheng-Han
The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title_full The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title_fullStr The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title_full_unstemmed The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title_short The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
title_sort impact of compulsivity and impulsivity in cerebellar ataxia: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583703/
https://www.ncbi.nlm.nih.gov/pubmed/33133767
http://dx.doi.org/10.5334/tohm.550
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