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Effect of TTLL12 on tubulin tyrosine nitration as a novel target for screening anticancer drugs in vitro

Nitrotyrosine, a structural analogue of tyrosine, is present in cells in pathological conditions and is incorporated into tubulin to form tubulin tyrosine nitration, which disrupts the normal function of microtubules. There is limited research on the functional aspects of tubulin tyrosine nitration...

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Detalles Bibliográficos
Autores principales: Xue, Lingli, Zeng, Yan, Fang, Chuan, Cheng, Wei, Li, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583732/
https://www.ncbi.nlm.nih.gov/pubmed/33123251
http://dx.doi.org/10.3892/ol.2020.12203