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Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA

An increased understanding of low-density lipoprotein receptor (LDLR) and its regulation may facilitate drug development for the treatment of hypercholesterolemia. Triciribine (TCN), which is a highly selective AKT inhibitor, increases the stability of LDLR mRNA downstream of extracellular signal-re...

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Detalles Bibliográficos
Autor principal:	Sundvold, Hilde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583736/ https://www.ncbi.nlm.nih.gov/pubmed/33019656 http://dx.doi.org/10.3390/molecules25194505

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