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Low PTEN expression and overexpression of phosphorylated Akt(Ser473) and Akt(Thr308) are associated with poor overall survival in upper tract urothelial carcinoma

The PI3K/Akt signaling pathway serves an essential role in various cellular processes, including cell growth, survival, cell motility, angiogenesis and cell metabolism. Loss of PTEN expression and hyperactivation of Akt can result in tumorigenesis. Previous studies observed expression of the Akt pro...

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Detalles Bibliográficos
Autores principales:	Weng, Wen-Hui, Yu, Kai-Jie, Li, Liang-Chen, Pang, Yeu-Jye, Chen, Ying-Tzu, Pang, See-Tong, Chuang, Cheng-Keng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583738/ https://www.ncbi.nlm.nih.gov/pubmed/33123258 http://dx.doi.org/10.3892/ol.2020.12210

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