Comparative Findings Between (68)Ga-PSMA and (18)F-FDG PET/CT for Hepatocellular Carcinoma

We have reported here the case of a 69-year-old man who presented with spinal cord compression due to bone metastases as the first manifestation of hepatocellular carcinoma (HCC). For the initial staging, the patient underwent (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computerized...

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Detalles Bibliográficos
Autores principales: Erhamamcı, Seval, Aslan, Nesrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583742/
https://www.ncbi.nlm.nih.gov/pubmed/33094578
http://dx.doi.org/10.4274/mirt.galenos.2020.50455
Descripción
Sumario:We have reported here the case of a 69-year-old man who presented with spinal cord compression due to bone metastases as the first manifestation of hepatocellular carcinoma (HCC). For the initial staging, the patient underwent (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) imaging, which demonstrated mild (18)F-FDG uptake in the multiple expansile osteolytic bone lesions, but no remarkable atypical (18)F-FDG uptake in the liver lesion on low-doses CT. An additional PET/CT scan was performed to evaluate the prostate-specific membrane antigen (PSMA) expression, which has recently been reported to be a potential biological marker in a variety of tumors including HCC. High PSMA uptake was recorded in both the metastatic bone lesions and the primary liver lesion/tumor by the (68)Ga-PSMA PET/CT.

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