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Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation

OBJECTIVES: Gallium-67 (Ga-67) imaging is affected by collimator penetration and scatter components owing to the high-energy (HE) gamma-ray emissions. The characterization of penetration and scatter distribution is essential for the optimization of low-energy high-resolution (LEHR), medium energy (M...

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Autores principales: Ouahman, Mina, Errifai, Rachid, Asmi, Hicham, Bouzekraoui, Youssef, Douama, Sanae, Bentayeb, Farida, Bonutti, Faustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583743/
https://www.ncbi.nlm.nih.gov/pubmed/33094575
http://dx.doi.org/10.4274/mirt.galenos.2020.21549
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author Ouahman, Mina
Errifai, Rachid
Asmi, Hicham
Bouzekraoui, Youssef
Douama, Sanae
Bentayeb, Farida
Bonutti, Faustino
author_facet Ouahman, Mina
Errifai, Rachid
Asmi, Hicham
Bouzekraoui, Youssef
Douama, Sanae
Bentayeb, Farida
Bonutti, Faustino
author_sort Ouahman, Mina
collection PubMed
description OBJECTIVES: Gallium-67 (Ga-67) imaging is affected by collimator penetration and scatter components owing to the high-energy (HE) gamma-ray emissions. The characterization of penetration and scatter distribution is essential for the optimization of low-energy high-resolution (LEHR), medium energy (ME), and HE collimators and for the development of an effective correction technique. We compared the image quality that can be achieved by 3 collimators for different energy windows using the SIMIND Monte Carlo code. METHODS: Simulation experiments were conducted for LEHR, ME, and HE collimators for Ga-67 point source placed at 12-cm distance from the detector surface using the Monte Carlo SIMIND simulation code. Their spectra point spread functions as well as the original, penetration, scattering, and X-rays curves were drawn and analyzed. The parameters full-width at half maximum and full-width at tenth maximum were also investigated. RESULTS: The original, penetration, and scatter curves within 10% for LEHR were 34.46%, 33.52%, 17.29%, and 14.72%, respectively. Similarly, the original, penetration, scatter, and X-rays within 10% for ME and HE were 83.06%, 10.25%, 6.69%, and 0% and 81.44%, 11.51%, 7.05%, and 0%, respectively. The trade-off between spatial resolution and sensitivity was achieved by using the ME collimator at 185 photopeak of Ga-67. CONCLUSION: The Monte Carlo simulation outcomes can be applied for optimal collimator designing and for the development of new correction method in Ga-67 imaging.
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spelling pubmed-75837432020-11-03 Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation Ouahman, Mina Errifai, Rachid Asmi, Hicham Bouzekraoui, Youssef Douama, Sanae Bentayeb, Farida Bonutti, Faustino Mol Imaging Radionucl Ther Original Article OBJECTIVES: Gallium-67 (Ga-67) imaging is affected by collimator penetration and scatter components owing to the high-energy (HE) gamma-ray emissions. The characterization of penetration and scatter distribution is essential for the optimization of low-energy high-resolution (LEHR), medium energy (ME), and HE collimators and for the development of an effective correction technique. We compared the image quality that can be achieved by 3 collimators for different energy windows using the SIMIND Monte Carlo code. METHODS: Simulation experiments were conducted for LEHR, ME, and HE collimators for Ga-67 point source placed at 12-cm distance from the detector surface using the Monte Carlo SIMIND simulation code. Their spectra point spread functions as well as the original, penetration, scattering, and X-rays curves were drawn and analyzed. The parameters full-width at half maximum and full-width at tenth maximum were also investigated. RESULTS: The original, penetration, and scatter curves within 10% for LEHR were 34.46%, 33.52%, 17.29%, and 14.72%, respectively. Similarly, the original, penetration, scatter, and X-rays within 10% for ME and HE were 83.06%, 10.25%, 6.69%, and 0% and 81.44%, 11.51%, 7.05%, and 0%, respectively. The trade-off between spatial resolution and sensitivity was achieved by using the ME collimator at 185 photopeak of Ga-67. CONCLUSION: The Monte Carlo simulation outcomes can be applied for optimal collimator designing and for the development of new correction method in Ga-67 imaging. Galenos Publishing 2020-10 2020-10-19 /pmc/articles/PMC7583743/ /pubmed/33094575 http://dx.doi.org/10.4274/mirt.galenos.2020.21549 Text en ©Copyright 2020 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ouahman, Mina
Errifai, Rachid
Asmi, Hicham
Bouzekraoui, Youssef
Douama, Sanae
Bentayeb, Farida
Bonutti, Faustino
Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title_full Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title_fullStr Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title_full_unstemmed Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title_short Collimator and Energy Window Evaluation in Ga-67 Imaging by Monte Carlo Simulation
title_sort collimator and energy window evaluation in ga-67 imaging by monte carlo simulation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583743/
https://www.ncbi.nlm.nih.gov/pubmed/33094575
http://dx.doi.org/10.4274/mirt.galenos.2020.21549
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