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Deep immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy

BACKGROUND: Although immune checkpoint blockade is effective for several malignancies, a substantial number of patients remain refractory to treatment. The future of immunotherapy will be a personalized approach adapted to each patient’s cancer-immune interactions in the tumor microenvironment (TME)...

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Detalles Bibliográficos
Autores principales:	Nagaoka, Koji, Shirai, Masataka, Taniguchi, Kiyomi, Hosoi, Akihiro, Sun, Changbo, Kobayashi, Yukari, Maejima, Kazuhiro, Fujita, Masashi, Nakagawa, Hidewaki, Nomura, Sachiyo, Kakimi, Kazuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583806/ https://www.ncbi.nlm.nih.gov/pubmed/33093158 http://dx.doi.org/10.1136/jitc-2020-001358

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