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The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen

The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, whic...

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Detalles Bibliográficos
Autores principales: Kiouptsi, Klytaimnistra, Jäckel, Sven, Wilms, Eivor, Pontarollo, Giulia, Winterstein, Jana, Karwot, Cornelia, Groß, Kathrin, Jurk, Kerstin, Reinhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583822/
https://www.ncbi.nlm.nih.gov/pubmed/32998468
http://dx.doi.org/10.3390/ijms21197171

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