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Atomistic Structure and Dynamics of the Ca(2+)-ATPase Bound to Phosphorylated Phospholamban

Sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) and phospholamban (PLB) are essential components of the cardiac Ca(2+) transport machinery. PLB phosphorylation at residue Ser16 (pSer16) enhances SERCA activity in the heart via an unknown structural mechanism. Here, we report a fully atomistic model of...

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Detalles Bibliográficos
Autores principales:	Aguayo-Ortiz, Rodrigo, Espinoza-Fonseca, L. Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583845/ https://www.ncbi.nlm.nih.gov/pubmed/33019581 http://dx.doi.org/10.3390/ijms21197261

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