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E2F1在常见肿瘤中的最新研究进展
The cell cycle-related transcription factor E2F1 is a member of the cell cycle-related transcription factor E2F family, mainly involved in various cell processes including cell cycle progression, DNA repair, DNA replication, cell differentiation, proliferation, and apoptosis. E2F1 is highly expresse...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583875/ https://www.ncbi.nlm.nih.gov/pubmed/33070516 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.32 |
| _version_ | 1783599478279766016 |
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| collection | PubMed |
| description | The cell cycle-related transcription factor E2F1 is a member of the cell cycle-related transcription factor E2F family, mainly involved in various cell processes including cell cycle progression, DNA repair, DNA replication, cell differentiation, proliferation, and apoptosis. E2F1 is highly expressed in a variety of tumor tissues and cells, and it plays a role as a cancer-promoting gene. The up-regulation of E2F1 expression is closely related to the occurrence, development, metastasis and prognosis of tumors. Therefore, E2F1 is expected to become a new target for cancer treatment. This article reviews the latest research progress of E2F1 in current common tumors. |
| format | Online Article Text |
| id | pubmed-7583875 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-75838752020-11-02 E2F1在常见肿瘤中的最新研究进展 Zhongguo Fei Ai Za Zhi 综述 The cell cycle-related transcription factor E2F1 is a member of the cell cycle-related transcription factor E2F family, mainly involved in various cell processes including cell cycle progression, DNA repair, DNA replication, cell differentiation, proliferation, and apoptosis. E2F1 is highly expressed in a variety of tumor tissues and cells, and it plays a role as a cancer-promoting gene. The up-regulation of E2F1 expression is closely related to the occurrence, development, metastasis and prognosis of tumors. Therefore, E2F1 is expected to become a new target for cancer treatment. This article reviews the latest research progress of E2F1 in current common tumors. 中国肺癌杂志编辑部 2020-10-20 /pmc/articles/PMC7583875/ /pubmed/33070516 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.32 Text en 版权所有©《中国肺癌杂志》编辑部2020 This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/. |
| spellingShingle | 综述 E2F1在常见肿瘤中的最新研究进展 |
| title | E2F1在常见肿瘤中的最新研究进展 |
| title_full | E2F1在常见肿瘤中的最新研究进展 |
| title_fullStr | E2F1在常见肿瘤中的最新研究进展 |
| title_full_unstemmed | E2F1在常见肿瘤中的最新研究进展 |
| title_short | E2F1在常见肿瘤中的最新研究进展 |
| title_sort | e2f1在常见肿瘤中的最新研究进展 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583875/ https://www.ncbi.nlm.nih.gov/pubmed/33070516 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.32 |
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