Cargando…

Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia

Gonorrhoea cases in women have been rising in Australia in the 2010s but the cause of the increase is not well understood. This cross-sectional study aimed to describe the characteristics of genital gonorrhoea infection in women attending the Melbourne Sexual Health Centre, Australia. Gonorrhoea cas...

Descripción completa

Detalles Bibliográficos
Autores principales: Martín-Sánchez, Mario, Fairley, Christopher K., Ong, Jason J., Maddaford, Kate, Chen, Marcus Y., Williamson, Deborah A., Bradshaw, Catriona S., Chow, Eric P.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584007/
https://www.ncbi.nlm.nih.gov/pubmed/32985394
http://dx.doi.org/10.1017/S0950268820002265
_version_ 1783599509801009152
author Martín-Sánchez, Mario
Fairley, Christopher K.
Ong, Jason J.
Maddaford, Kate
Chen, Marcus Y.
Williamson, Deborah A.
Bradshaw, Catriona S.
Chow, Eric P.F.
author_facet Martín-Sánchez, Mario
Fairley, Christopher K.
Ong, Jason J.
Maddaford, Kate
Chen, Marcus Y.
Williamson, Deborah A.
Bradshaw, Catriona S.
Chow, Eric P.F.
author_sort Martín-Sánchez, Mario
collection PubMed
description Gonorrhoea cases in women have been rising in Australia in the 2010s but the cause of the increase is not well understood. This cross-sectional study aimed to describe the characteristics of genital gonorrhoea infection in women attending the Melbourne Sexual Health Centre, Australia. Gonorrhoea cases were diagnosed by nucleic acid amplification test (NAAT) and/or culture. Genitourinary specimens were obtained in 12 869 clinic visits in women aged 16 years or above between August 2017 and August 2018. Genital gonorrhoea was detected in 142 (1.1%) of the visits. Almost half of the cases were asymptomatic, 47.9% [95% confidence interval (CI) 39.8–56.1%]; yellow, green or pus-like vaginal discharge was present in 11.3% (95% CI 7.0–17.6%) and other genital symptoms in 40.8% (95% CI 33.1–49.1%) of the cases. The mean time between last sexual contact and onset of symptoms was 7.3 days and between the onset of symptoms to presentation to the clinic was 12.1 days. Half of the cases of genital gonorrhoea among women are asymptomatic and these cases would have been missed by testing of only symptomatic women. Further epidemiological and behavioural research is required to understand the temporal changes in sexual practices among women in Australia.
format Online
Article
Text
id pubmed-7584007
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cambridge University Press
record_format MEDLINE/PubMed
spelling pubmed-75840072020-11-03 Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia Martín-Sánchez, Mario Fairley, Christopher K. Ong, Jason J. Maddaford, Kate Chen, Marcus Y. Williamson, Deborah A. Bradshaw, Catriona S. Chow, Eric P.F. Epidemiol Infect Original Paper Gonorrhoea cases in women have been rising in Australia in the 2010s but the cause of the increase is not well understood. This cross-sectional study aimed to describe the characteristics of genital gonorrhoea infection in women attending the Melbourne Sexual Health Centre, Australia. Gonorrhoea cases were diagnosed by nucleic acid amplification test (NAAT) and/or culture. Genitourinary specimens were obtained in 12 869 clinic visits in women aged 16 years or above between August 2017 and August 2018. Genital gonorrhoea was detected in 142 (1.1%) of the visits. Almost half of the cases were asymptomatic, 47.9% [95% confidence interval (CI) 39.8–56.1%]; yellow, green or pus-like vaginal discharge was present in 11.3% (95% CI 7.0–17.6%) and other genital symptoms in 40.8% (95% CI 33.1–49.1%) of the cases. The mean time between last sexual contact and onset of symptoms was 7.3 days and between the onset of symptoms to presentation to the clinic was 12.1 days. Half of the cases of genital gonorrhoea among women are asymptomatic and these cases would have been missed by testing of only symptomatic women. Further epidemiological and behavioural research is required to understand the temporal changes in sexual practices among women in Australia. Cambridge University Press 2020-09-28 /pmc/articles/PMC7584007/ /pubmed/32985394 http://dx.doi.org/10.1017/S0950268820002265 Text en © The Author(s) 2020 http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Martín-Sánchez, Mario
Fairley, Christopher K.
Ong, Jason J.
Maddaford, Kate
Chen, Marcus Y.
Williamson, Deborah A.
Bradshaw, Catriona S.
Chow, Eric P.F.
Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title_full Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title_fullStr Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title_full_unstemmed Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title_short Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia
title_sort clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in melbourne, australia
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584007/
https://www.ncbi.nlm.nih.gov/pubmed/32985394
http://dx.doi.org/10.1017/S0950268820002265
work_keys_str_mv AT martinsanchezmario clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT fairleychristopherk clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT ongjasonj clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT maddafordkate clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT chenmarcusy clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT williamsondeboraha clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT bradshawcatrionas clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia
AT chowericpf clinicalpresentationofasymptomaticandsymptomaticwomenwhotestedpositiveforgenitalgonorrhoeaatasexualhealthserviceinmelbourneaustralia