Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita

Dyskeratosis congenita (DKC) is a rare inherited disease of impaired telomere maintenance that progressively leads to multi-organ failure, including the bone marrow. By enhancing telomerase activity, androgen derivatives (ADs) are a potential therapeutic option able to re-elongate previously shorten...

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Detalles Bibliográficos
Autores principales: Vieri, Margherita, Kirschner, Martin, Tometten, Mareike, Abels, Anne, Rolles, Benjamin, Isfort, Susanne, Panse, Jens, Brümmendorf, Tim H., Beier, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584039/
https://www.ncbi.nlm.nih.gov/pubmed/33003434
http://dx.doi.org/10.3390/ijms21197196

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