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Single access laparoscopic total colectomy for severe refractory ulcerative colitis

BACKGROUND: Single port laparoscopic surgery allows total colectomy and end ileostomy for medically uncontrolled ulcerative colitis solely via the stoma site incision. While intuitively appealing, there is sparse evidence for its use beyond feasibility. AIM: To examine the usefulness of single acces...

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Autores principales: Burke, John, Toomey, Des, Reilly, Frank, Cahill, Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584061/
https://www.ncbi.nlm.nih.gov/pubmed/33132651
http://dx.doi.org/10.3748/wjg.v26.i39.6015
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author Burke, John
Toomey, Des
Reilly, Frank
Cahill, Ronan
author_facet Burke, John
Toomey, Des
Reilly, Frank
Cahill, Ronan
author_sort Burke, John
collection PubMed
description BACKGROUND: Single port laparoscopic surgery allows total colectomy and end ileostomy for medically uncontrolled ulcerative colitis solely via the stoma site incision. While intuitively appealing, there is sparse evidence for its use beyond feasibility. AIM: To examine the usefulness of single access laparoscopy (SAL) in a general series experience of patients sick with ulcerative colitis. METHODS: All patients presenting electively, urgently or emergently over a three-year period under a colorectal specialist team were studied. SAL was performed via the stoma site on a near-consecutive basis by one surgical team using a “surgical glove port” allowing group-comparative and case-control analysis with a contemporary cohort undergoing conventional multiport surgery. Standard, straight rigid laparoscopic instrumentation were used without additional resource. RESULTS: Of 46 consecutive patients requiring surgery, 39 (85%) had their procedure begun laparoscopically. 27 (69%) of these were commenced by single port access with an 89% completion rate thereafter (three were concluded by multi-trocar laparoscopy). SAL proved effective in comparison to multiport access regardless of disease severity providing significantly reduced operative access costs (> 100€case) and postoperative hospital stay (median 5 d vs 7.5 d, P = 0.045) without increasing operative time. It proved especially efficient in those with preoperative albumin > 30 g/dL (n = 20). Its comparative advantages were further confirmed in ten pairs case-matched for gender, body mass index and preoperative albumin. SAL outcomes proved durable in the intermediate term (median follow-up = 20 mo). CONCLUSION: Single port total colectomy proved useful in planned and acute settings for patients with medically refractory colitis. Assumptions regarding duration and cost should not be barriers to its implementation.
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spelling pubmed-75840612020-10-30 Single access laparoscopic total colectomy for severe refractory ulcerative colitis Burke, John Toomey, Des Reilly, Frank Cahill, Ronan World J Gastroenterol Case Control Study BACKGROUND: Single port laparoscopic surgery allows total colectomy and end ileostomy for medically uncontrolled ulcerative colitis solely via the stoma site incision. While intuitively appealing, there is sparse evidence for its use beyond feasibility. AIM: To examine the usefulness of single access laparoscopy (SAL) in a general series experience of patients sick with ulcerative colitis. METHODS: All patients presenting electively, urgently or emergently over a three-year period under a colorectal specialist team were studied. SAL was performed via the stoma site on a near-consecutive basis by one surgical team using a “surgical glove port” allowing group-comparative and case-control analysis with a contemporary cohort undergoing conventional multiport surgery. Standard, straight rigid laparoscopic instrumentation were used without additional resource. RESULTS: Of 46 consecutive patients requiring surgery, 39 (85%) had their procedure begun laparoscopically. 27 (69%) of these were commenced by single port access with an 89% completion rate thereafter (three were concluded by multi-trocar laparoscopy). SAL proved effective in comparison to multiport access regardless of disease severity providing significantly reduced operative access costs (> 100€case) and postoperative hospital stay (median 5 d vs 7.5 d, P = 0.045) without increasing operative time. It proved especially efficient in those with preoperative albumin > 30 g/dL (n = 20). Its comparative advantages were further confirmed in ten pairs case-matched for gender, body mass index and preoperative albumin. SAL outcomes proved durable in the intermediate term (median follow-up = 20 mo). CONCLUSION: Single port total colectomy proved useful in planned and acute settings for patients with medically refractory colitis. Assumptions regarding duration and cost should not be barriers to its implementation. Baishideng Publishing Group Inc 2020-10-21 2020-10-21 /pmc/articles/PMC7584061/ /pubmed/33132651 http://dx.doi.org/10.3748/wjg.v26.i39.6015 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Control Study
Burke, John
Toomey, Des
Reilly, Frank
Cahill, Ronan
Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title_full Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title_fullStr Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title_full_unstemmed Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title_short Single access laparoscopic total colectomy for severe refractory ulcerative colitis
title_sort single access laparoscopic total colectomy for severe refractory ulcerative colitis
topic Case Control Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584061/
https://www.ncbi.nlm.nih.gov/pubmed/33132651
http://dx.doi.org/10.3748/wjg.v26.i39.6015
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