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Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing

BACKGROUND: Scar formation, which may be caused by myofibroblast aggregations, is the greatest challenge during skin wound healing in the clinical setting. Studies have indicated that epidermal stem cells (EPSC) improve wound healing and reduce scar formation. METHODS: We investigated the therapeuti...

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Detalles Bibliográficos
Autores principales: Duan, Mengna, Zhang, Yan, Zhang, Haiyang, Meng, Yupeng, Qian, Ming, Zhang, Guokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584097/
https://www.ncbi.nlm.nih.gov/pubmed/33097078
http://dx.doi.org/10.1186/s13287-020-01971-6