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TRAIL receptor agonists convert the response of breast cancer cells to ONC201 from anti-proliferative to apoptotic
ONC201 was initially identified as an inducer of cell death through the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway. The compound is currently being tested in patients with hematological malignancies and solid tumors, including those of the breast. We investigated strateg...
Autores principales: | Ralff, Marie D., Jhaveri, Aakash, Ray, Jocelyn E., Zhou, Lanlan, Lev, Avital, Campbell, Kerry S., Dicker, David T., Ross, Eric A., El-Deiry, Wafik S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584235/ https://www.ncbi.nlm.nih.gov/pubmed/33144917 http://dx.doi.org/10.18632/oncotarget.27773 |
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