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Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis

Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was...

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Autores principales: Savino, Manuela, Casula, Anna, Santhakumaran, Shalini, Pitcher, David, Wong, Esther, Magadi, Winnie, Evans, Katharine M., Benoy-Deeney, Fran, Griffin, James, Plumb, Lucy, Steenkamp, Retha, Nitsch, Dorothea, Medcalf, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584244/
https://www.ncbi.nlm.nih.gov/pubmed/33095841
http://dx.doi.org/10.1371/journal.pone.0241263
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author Savino, Manuela
Casula, Anna
Santhakumaran, Shalini
Pitcher, David
Wong, Esther
Magadi, Winnie
Evans, Katharine M.
Benoy-Deeney, Fran
Griffin, James
Plumb, Lucy
Steenkamp, Retha
Nitsch, Dorothea
Medcalf, James
author_facet Savino, Manuela
Casula, Anna
Santhakumaran, Shalini
Pitcher, David
Wong, Esther
Magadi, Winnie
Evans, Katharine M.
Benoy-Deeney, Fran
Griffin, James
Plumb, Lucy
Steenkamp, Retha
Nitsch, Dorothea
Medcalf, James
author_sort Savino, Manuela
collection PubMed
description Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1–88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94–1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group.
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spelling pubmed-75842442020-10-28 Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis Savino, Manuela Casula, Anna Santhakumaran, Shalini Pitcher, David Wong, Esther Magadi, Winnie Evans, Katharine M. Benoy-Deeney, Fran Griffin, James Plumb, Lucy Steenkamp, Retha Nitsch, Dorothea Medcalf, James PLoS One Research Article Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1–88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94–1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group. Public Library of Science 2020-10-23 /pmc/articles/PMC7584244/ /pubmed/33095841 http://dx.doi.org/10.1371/journal.pone.0241263 Text en © 2020 Savino et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Savino, Manuela
Casula, Anna
Santhakumaran, Shalini
Pitcher, David
Wong, Esther
Magadi, Winnie
Evans, Katharine M.
Benoy-Deeney, Fran
Griffin, James
Plumb, Lucy
Steenkamp, Retha
Nitsch, Dorothea
Medcalf, James
Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title_full Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title_fullStr Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title_full_unstemmed Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title_short Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
title_sort sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for sars-cov-2: a uk renal registry data analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584244/
https://www.ncbi.nlm.nih.gov/pubmed/33095841
http://dx.doi.org/10.1371/journal.pone.0241263
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