Cargando…
Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis
Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584244/ https://www.ncbi.nlm.nih.gov/pubmed/33095841 http://dx.doi.org/10.1371/journal.pone.0241263 |
_version_ | 1783599558157139968 |
---|---|
author | Savino, Manuela Casula, Anna Santhakumaran, Shalini Pitcher, David Wong, Esther Magadi, Winnie Evans, Katharine M. Benoy-Deeney, Fran Griffin, James Plumb, Lucy Steenkamp, Retha Nitsch, Dorothea Medcalf, James |
author_facet | Savino, Manuela Casula, Anna Santhakumaran, Shalini Pitcher, David Wong, Esther Magadi, Winnie Evans, Katharine M. Benoy-Deeney, Fran Griffin, James Plumb, Lucy Steenkamp, Retha Nitsch, Dorothea Medcalf, James |
author_sort | Savino, Manuela |
collection | PubMed |
description | Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1–88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94–1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group. |
format | Online Article Text |
id | pubmed-7584244 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-75842442020-10-28 Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis Savino, Manuela Casula, Anna Santhakumaran, Shalini Pitcher, David Wong, Esther Magadi, Winnie Evans, Katharine M. Benoy-Deeney, Fran Griffin, James Plumb, Lucy Steenkamp, Retha Nitsch, Dorothea Medcalf, James PLoS One Research Article Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1–88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94–1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group. Public Library of Science 2020-10-23 /pmc/articles/PMC7584244/ /pubmed/33095841 http://dx.doi.org/10.1371/journal.pone.0241263 Text en © 2020 Savino et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Savino, Manuela Casula, Anna Santhakumaran, Shalini Pitcher, David Wong, Esther Magadi, Winnie Evans, Katharine M. Benoy-Deeney, Fran Griffin, James Plumb, Lucy Steenkamp, Retha Nitsch, Dorothea Medcalf, James Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title | Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title_full | Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title_fullStr | Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title_full_unstemmed | Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title_short | Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis |
title_sort | sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for sars-cov-2: a uk renal registry data analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584244/ https://www.ncbi.nlm.nih.gov/pubmed/33095841 http://dx.doi.org/10.1371/journal.pone.0241263 |
work_keys_str_mv | AT savinomanuela sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT casulaanna sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT santhakumaranshalini sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT pitcherdavid sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT wongesther sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT magadiwinnie sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT evanskatharinem sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT benoydeeneyfran sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT griffinjames sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT plumblucy sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT steenkampretha sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT nitschdorothea sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis AT medcalfjames sociodemographicfeaturesandmortalityofindividualsonhaemodialysistreatmentwhotestpositiveforsarscov2aukrenalregistrydataanalysis |