Cargando…

Cytotoxic T-cells mediate exercise-induced reductions in tumor growth

Exercise has a wide range of systemic effects. In animal models, repeated exertion reduces malignant tumor progression, and clinically, exercise can improve outcome for cancer patients. The etiology of the effects of exercise on tumor progression are unclear, as are the cellular actors involved. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rundqvist, Helene, Veliça, Pedro, Barbieri, Laura, Gameiro, Paulo A, Bargiela, David, Gojkovic, Milos, Mijwel, Sara, Reitzner, Stefan Markus, Wulliman, David, Ahlstedt, Emil, Ule, Jernej, Östman, Arne, Johnson, Randall S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584454/ https://www.ncbi.nlm.nih.gov/pubmed/33095157 http://dx.doi.org/10.7554/eLife.59996

Ejemplares similares

Deregulated hypoxic response in myeloid cells: A model for high‐altitude pulmonary oedema (HAPE)
por: Gojkovic, Milos, et al.
Publicado: (2020)

Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation
por: Gojkovic, Milos, et al.
Publicado: (2021)

Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells
por: Barbieri, Laura, et al.
Publicado: (2023)

Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses
por: Bargiela, David, et al.
Publicado: (2022)

Effects of Exercise on Chemotherapy Completion and Hospitalization Rates: The OptiTrain Breast Cancer Trial
por: Mijwel, Sara, et al.
Publicado: (2019)

Inflammation Mediates Exercise Effects on Fatigue in Patients with Breast Cancer
por: HIENSCH, ANOUK E., et al.
Publicado: (2021)

Effect of Acute Exercise on Prostate Cancer Cell Growth
por: Rundqvist, Helene, et al.
Publicado: (2013)

Infiltration of Tumors Is Regulated by T cell–Intrinsic Nitric Oxide Synthesis
por: Cunha, Pedro P., et al.
Publicado: (2023)

Fibroblasts—a key host cell type in tumor initiation, progression, and metastasis
por: Strell, Carina, et al.
Publicado: (2012)

Glycolytic Response to Inflammation Over Time: Role of Myeloid HIF-1alpha
por: Fitzpatrick, Susan F., et al.
Publicado: (2018)

Two-year follow-up of the OptiTrain randomised controlled exercise trial
por: Bolam, Kate A., et al.
Publicado: (2019)

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
por: Palazon, Asis, et al.
Publicado: (2017)

Physical Activity During and After Adjuvant Treatment for Breast Cancer: An Integrative Review of Women’s Experiences
por: Browall, Maria, et al.
Publicado: (2016)

Highly favorable physiological responses to concurrent resistance and high-intensity interval training during chemotherapy: the OptiTrain breast cancer trial
por: Mijwel, Sara, et al.
Publicado: (2018)

Validation of 2 Submaximal Cardiorespiratory Fitness Tests in Patients With Breast Cancer Undergoing Chemotherapy
por: Mijwel, Sara, et al.
Publicado: (2016)

High-intensity exercise during chemotherapy induces beneficial effects 12 months into breast cancer survivorship
por: Mijwel, Sara, et al.
Publicado: (2019)

High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT
por: Ansund, Josefin, et al.
Publicado: (2021)

Metabolic turnover and dynamics of modified ribonucleosides by (13)C labeling
por: Gameiro, Paulo A., et al.
Publicado: (2021)

Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy
por: Cunha, Pedro P, et al.
Publicado: (2023)

Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells
por: Cheteh, Emarndeena H., et al.
Publicado: (2020)

Alu elements: at the crossroads between disease and evolution
por: Ule, Jernej
Publicado: (2013)

Open access, open data and peer review
por: Ule, Jernej
Publicado: (2020)

Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial
por: Mijwel, Sara, et al.
Publicado: (2017)

Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
por: Cheteh, Emarndeena H, et al.
Publicado: (2017)

Long-Term Favorable Effects of Physical Exercise on Burdensome Symptoms in the OptiTrain Breast Cancer Randomized Controlled Trial
por: Wiggenraad, Fleur, et al.
Publicado: (2020)

Understanding splicing regulation through RNA splicing maps
por: Witten, Joshua T., et al.
Publicado: (2011)

Optitrain: a randomised controlled exercise trial for women with breast cancer undergoing chemotherapy
por: Wengström, Y., et al.
Publicado: (2017)

Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior
por: Yamamoto, Hideki, et al.
Publicado: (2016)

'Oming in on RNA–protein interactions
por: Rinn, John L, et al.
Publicado: (2014)

Identification of prediagnostic metabolites associated with prostate cancer risk by untargeted mass spectrometry‐based metabolomics: A case‐control study nested in the Northern Sweden Health and Disease Study
por: Östman, Johnny R., et al.
Publicado: (2022)

Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer
por: Mader, Theresa, et al.
Publicado: (2022)

Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice
por: Kantari-Mimoun, Chahrazade, et al.
Publicado: (2017)

Acute exercise mobilizes CD8(+) cytotoxic T cells and NK cells in lymphoma patients
por: Koivula, Tiia, et al.
Publicado: (2023)

‘Read–through marking’ reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP
por: Huppertz, Ina, et al.
Publicado: (2018)

Thromboembolic Events During Treatment with Cisplatin-based Chemotherapy in Metastatic Testicular Germ-cell Cancer 2000–2014: A Population-based Cohort Study
por: Haugnes, Hege S., et al.
Publicado: (2021)

The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine
por: Chidley, Christopher, et al.
Publicado: (2016)

Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity
por: Abedi, Marjan, et al.
Publicado: (2020)

Glutarate regulates T cell metabolism and anti-tumour immunity
por: Minogue, Eleanor, et al.
Publicado: (2023)

CLIPing the brain: Studies of protein–RNA interactions important for neurodegenerative disorders()()
por: Modic, Miha, et al.
Publicado: (2013)

What, where, and when: the importance of post-transcriptional regulation in the brain
por: Kiebler, Michael A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4ieeduvdh7hfrn25bv6ummd21n