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The effect of hybridization on transposable element accumulation in an undomesticated fungal species
Transposable elements (TEs) are mobile genetic elements that can profoundly impact the evolution of genomes and species. A long-standing hypothesis suggests that hybridization could deregulate TEs and trigger their accumulation, although it received mixed support from studies mostly in plants and an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584455/ https://www.ncbi.nlm.nih.gov/pubmed/32955438 http://dx.doi.org/10.7554/eLife.60474 |
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author | Hénault, Mathieu Marsit, Souhir Charron, Guillaume Landry, Christian R |
author_facet | Hénault, Mathieu Marsit, Souhir Charron, Guillaume Landry, Christian R |
author_sort | Hénault, Mathieu |
collection | PubMed |
description | Transposable elements (TEs) are mobile genetic elements that can profoundly impact the evolution of genomes and species. A long-standing hypothesis suggests that hybridization could deregulate TEs and trigger their accumulation, although it received mixed support from studies mostly in plants and animals. Here, we tested this hypothesis in fungi using incipient species of the undomesticated yeast Saccharomyces paradoxus. Population genomic data revealed no signature of higher transposition in natural hybrids. As we could not rule out the elimination of past transposition increase signatures by natural selection, we performed a laboratory evolution experiment on a panel of artificial hybrids to measure TE accumulation in the near absence of selection. Changes in TE copy numbers were not predicted by the level of evolutionary divergence between the parents of a hybrid genotype. Rather, they were highly dependent on the individual hybrid genotypes, showing that strong genotype-specific deterministic factors govern TE accumulation in yeast hybrids. |
format | Online Article Text |
id | pubmed-7584455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-75844552020-10-28 The effect of hybridization on transposable element accumulation in an undomesticated fungal species Hénault, Mathieu Marsit, Souhir Charron, Guillaume Landry, Christian R eLife Evolutionary Biology Transposable elements (TEs) are mobile genetic elements that can profoundly impact the evolution of genomes and species. A long-standing hypothesis suggests that hybridization could deregulate TEs and trigger their accumulation, although it received mixed support from studies mostly in plants and animals. Here, we tested this hypothesis in fungi using incipient species of the undomesticated yeast Saccharomyces paradoxus. Population genomic data revealed no signature of higher transposition in natural hybrids. As we could not rule out the elimination of past transposition increase signatures by natural selection, we performed a laboratory evolution experiment on a panel of artificial hybrids to measure TE accumulation in the near absence of selection. Changes in TE copy numbers were not predicted by the level of evolutionary divergence between the parents of a hybrid genotype. Rather, they were highly dependent on the individual hybrid genotypes, showing that strong genotype-specific deterministic factors govern TE accumulation in yeast hybrids. eLife Sciences Publications, Ltd 2020-09-21 /pmc/articles/PMC7584455/ /pubmed/32955438 http://dx.doi.org/10.7554/eLife.60474 Text en © 2020, Hénault et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Evolutionary Biology Hénault, Mathieu Marsit, Souhir Charron, Guillaume Landry, Christian R The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title | The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title_full | The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title_fullStr | The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title_full_unstemmed | The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title_short | The effect of hybridization on transposable element accumulation in an undomesticated fungal species |
title_sort | effect of hybridization on transposable element accumulation in an undomesticated fungal species |
topic | Evolutionary Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584455/ https://www.ncbi.nlm.nih.gov/pubmed/32955438 http://dx.doi.org/10.7554/eLife.60474 |
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