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Manipulating the Mediator complex to induce naïve pluripotency

Human naïve pluripotent stem cells (PSCs) represent an optimal homogenous starting point for molecular interventions and differentiation strategies. This is in contrast to the standard primed PSCs which fluctuate in identity and are transcriptionally heterogeneous. However, despite many efforts, the...

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Detalles Bibliográficos
Autores principales: Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584500/
https://www.ncbi.nlm.nih.gov/pubmed/32771524
http://dx.doi.org/10.1016/j.yexcr.2020.112215