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Manipulating the Mediator complex to induce naïve pluripotency
Human naïve pluripotent stem cells (PSCs) represent an optimal homogenous starting point for molecular interventions and differentiation strategies. This is in contrast to the standard primed PSCs which fluctuate in identity and are transcriptionally heterogeneous. However, despite many efforts, the...
Autores principales: | Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Serrano, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584500/ https://www.ncbi.nlm.nih.gov/pubmed/32771524 http://dx.doi.org/10.1016/j.yexcr.2020.112215 |
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