Proteomic resolution of IGFN1 complexes reveals a functional interaction with the actin nucleating protein COBL

The Igfn1 gene produces multiple proteins by alternative splicing predominantly expressed in skeletal muscle. Igfn1 deficient clones derived from C2C12 myoblasts show reduced fusion index and morphological differences compared to control myotubes. Here, we first show that G:F actin ratios are signif...

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Detalles Bibliográficos
Autores principales: Cracknell, Tobias, Mannsverk, Steinar, Nichols, Angus, Dowle, Adam, Blanco, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584501/
https://www.ncbi.nlm.nih.gov/pubmed/32768501
http://dx.doi.org/10.1016/j.yexcr.2020.112179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584501/
https://www.ncbi.nlm.nih.gov/pubmed/32768501
http://dx.doi.org/10.1016/j.yexcr.2020.112179

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