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Proteomic resolution of IGFN1 complexes reveals a functional interaction with the actin nucleating protein COBL
The Igfn1 gene produces multiple proteins by alternative splicing predominantly expressed in skeletal muscle. Igfn1 deficient clones derived from C2C12 myoblasts show reduced fusion index and morphological differences compared to control myotubes. Here, we first show that G:F actin ratios are signif...
Autores principales: | Cracknell, Tobias, Mannsverk, Steinar, Nichols, Angus, Dowle, Adam, Blanco, Gonzalo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584501/ https://www.ncbi.nlm.nih.gov/pubmed/32768501 http://dx.doi.org/10.1016/j.yexcr.2020.112179 |
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