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Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study

PURPOSE: To evaluate eye rubbing and sleeping position in patients with Unilateral or Highly Asymmetric Keratoconus (UHAKC). METHODS: Case-control study of consecutive UHAKC patients diagnosed at the Rothschild Foundation. Controls were age- and sex-matched, randomly selected refractive surgery clin...

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Autores principales: Mazharian, Adrien, Panthier, Christophe, Courtin, Romain, Jung, Camille, Rampat, Radhika, Saad, Alain, Gatinel, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584543/
https://www.ncbi.nlm.nih.gov/pubmed/32524239
http://dx.doi.org/10.1007/s00417-020-04771-z
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author Mazharian, Adrien
Panthier, Christophe
Courtin, Romain
Jung, Camille
Rampat, Radhika
Saad, Alain
Gatinel, Damien
author_facet Mazharian, Adrien
Panthier, Christophe
Courtin, Romain
Jung, Camille
Rampat, Radhika
Saad, Alain
Gatinel, Damien
author_sort Mazharian, Adrien
collection PubMed
description PURPOSE: To evaluate eye rubbing and sleeping position in patients with Unilateral or Highly Asymmetric Keratoconus (UHAKC). METHODS: Case-control study of consecutive UHAKC patients diagnosed at the Rothschild Foundation. Controls were age- and sex-matched, randomly selected refractive surgery clinic patients. Patients self-administered questionnaires regarding their family history of keratoconus, eye rubbing, and sleeping habits. All the eyes underwent a comprehensive ocular examination. Logistic regression was used to analyze univariate and multivariate data to identify risk factors for keratoconus. RESULTS: Thirty-three UHAKC patients and 64 controls were included. Univariate analyses showed that daytime eye rubbing [OR = 172.78], in the morning [OR = 24.3], or in eyes with the steepest keratometry [OR = 21.7] were significantly different between groups. Allergy [OR = 2.94], red eyes in the morning [OR = 6.36], and sleeping on stomach/sides [OR = 14.31] or on the same side as the steepest keratometry [OR = 94.72] were also significantly different. The multivariate model also showed statistical significance for most factors including daytime eye rubbing [OR = 134.96], in the morning [OR = 24.86], in the steepest eye [OR = 27.56], and sleeping on stomach/sides [OR = 65.02] or on the steepest side [OR = 144.02]. A univariate analysis in UHAKC group, comparing the worse and better eye, showed that eye rubbing [OR = 162.14] and sleeping position [OR = 99.74] were significantly (p < 0.001) associated with the worse eye. CONCLUSION: Our data suggests that vigorous eye rubbing and incorrect sleeping position are associated with UHAKC. This is especially true in rubbing the most afflicted eye, and contributory sleep position, including positions placing pressure on the eye with the steepest keratometry. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00417-020-04771-z) contains supplementary material, which is available to authorized users.
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spelling pubmed-75845432020-10-27 Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study Mazharian, Adrien Panthier, Christophe Courtin, Romain Jung, Camille Rampat, Radhika Saad, Alain Gatinel, Damien Graefes Arch Clin Exp Ophthalmol Cornea PURPOSE: To evaluate eye rubbing and sleeping position in patients with Unilateral or Highly Asymmetric Keratoconus (UHAKC). METHODS: Case-control study of consecutive UHAKC patients diagnosed at the Rothschild Foundation. Controls were age- and sex-matched, randomly selected refractive surgery clinic patients. Patients self-administered questionnaires regarding their family history of keratoconus, eye rubbing, and sleeping habits. All the eyes underwent a comprehensive ocular examination. Logistic regression was used to analyze univariate and multivariate data to identify risk factors for keratoconus. RESULTS: Thirty-three UHAKC patients and 64 controls were included. Univariate analyses showed that daytime eye rubbing [OR = 172.78], in the morning [OR = 24.3], or in eyes with the steepest keratometry [OR = 21.7] were significantly different between groups. Allergy [OR = 2.94], red eyes in the morning [OR = 6.36], and sleeping on stomach/sides [OR = 14.31] or on the same side as the steepest keratometry [OR = 94.72] were also significantly different. The multivariate model also showed statistical significance for most factors including daytime eye rubbing [OR = 134.96], in the morning [OR = 24.86], in the steepest eye [OR = 27.56], and sleeping on stomach/sides [OR = 65.02] or on the steepest side [OR = 144.02]. A univariate analysis in UHAKC group, comparing the worse and better eye, showed that eye rubbing [OR = 162.14] and sleeping position [OR = 99.74] were significantly (p < 0.001) associated with the worse eye. CONCLUSION: Our data suggests that vigorous eye rubbing and incorrect sleeping position are associated with UHAKC. This is especially true in rubbing the most afflicted eye, and contributory sleep position, including positions placing pressure on the eye with the steepest keratometry. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00417-020-04771-z) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-06-10 2020 /pmc/articles/PMC7584543/ /pubmed/32524239 http://dx.doi.org/10.1007/s00417-020-04771-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Cornea
Mazharian, Adrien
Panthier, Christophe
Courtin, Romain
Jung, Camille
Rampat, Radhika
Saad, Alain
Gatinel, Damien
Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title_full Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title_fullStr Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title_full_unstemmed Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title_short Incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
title_sort incorrect sleeping position and eye rubbing in patients with unilateral or highly asymmetric keratoconus: a case-control study
topic Cornea
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584543/
https://www.ncbi.nlm.nih.gov/pubmed/32524239
http://dx.doi.org/10.1007/s00417-020-04771-z
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