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Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes

ABSTRACT: Native mass spectrometry is a potent technique to study and characterize biomacromolecules in their native state. Here, we have applied this method to explore the solution chemistry of human carbonic anhydrase I (hCA I) and its interactions with four different inhibitors, namely three sulf...

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Detalles Bibliográficos
Autores principales: Zoppi, Carlotta, Nocentini, Alessio, Supuran, Claudiu T., Pratesi, Alessandro, Messori, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584553/
https://www.ncbi.nlm.nih.gov/pubmed/32926233
http://dx.doi.org/10.1007/s00775-020-01818-8